منابع مشابه
The Crystal Structure of Toxoplasma gondii Pyruvate Kinase 1
BACKGROUND Pyruvate kinase (PK), which catalyzes the final step in glycolysis converting phosphoenolpyruvate to pyruvate, is a central metabolic regulator in most organisms. Consequently PK represents an attractive therapeutic target in cancer and human pathogens, like Apicomplexans. The phylum Aplicomplexa, a group of exclusively parasitic organisms, includes the genera Plasmodium, Cryptospori...
متن کاملPrevalence of Pyruvate Kinase Deficiency among the Newborns (Shiraz-Iran)
Background: The frequency of pyruvate kinase (PK) deficiency, an autosomal recessive defect, is approximately 3 per 10,000 individuals in Shiraz and surrounding areas, and is increased due to high consanguinity marriage frequency. The purpose of this study is to obtain data on the frequency and spectrum of gene mutation of PK in newborns, from Shiraz and surrounding areas. Materials and Methods...
متن کاملprevalence of pyruvate kinase deficiency among the newborns (shiraz-iran)
background: the frequency of pyruvate kinase (pk) deficiency, an autosomal recessive defect, is approximately 3 per 10,000 individuals in shiraz and surrounding areas, and is increased due to high consanguinity marriage frequency. the purpose of this study is to obtain data on the frequency and spectrum of gene mutation of pk in newborns, from shiraz and surrounding areas. materials and methods...
متن کاملIsoenzymes of pyruvate kinase
-. 1 3 . Miernyk. J. A. & Dennis. I>. 1 ( 1982) I’lurit I’hyxiol. 69. 825-828 Journet. E. P. & Douce. R. ( 1 984) (‘. K. Acud. Sci. /’(iris Ser. 111 298, 365-370 Hotha, F. C. & Dennis, D. R. ( 1986) Arch. Bioc,hem. Bioplrvs. 245.96I03 Fothergill. L. A. & Harkins. R. N . ( 1982) /’roc.. K. Soc. London H215, 19-44 White. M. F. & Fothergill-Gilmore. L. A. (1988) FEES Lett. 229,383-387 Winn. S. I.,...
متن کاملSpecificity of pyruvate kinase.
Short Communications Specificity of pyruvate kinase Previous reports have indicated that pyruvate kinase is a relatively non-specific enzyme capable of catalyzing the transfer of phosphate from PEP to a wide variety of nucleoside diphosphate acceptors l& In the present studies, attempts were made to utilize this enzyme for the assay of UDP.The rate of phosphate transfer to nucleoside diphosphat...
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ژورنال
عنوان ژورنال: Medical Entomology and Zoology
سال: 2001
ISSN: 0424-7086,2185-5609
DOI: 10.7601/mez.52.100_3